Executive Committee
President
Olivier HERAULT, MD, PhD
Professor of hematology
Tours university hospital, Tours
INSERM UMR1069
INSERM UMS61
OPALE Carnot Institute
- Ravalet N et al. Modulation of bone marrow and peripheral blood cytokine levels by age and clonal hematopoiesis in healthy individuals. Clin Immunol 2023, 255:109730.
- Roux B et al. Aberrant DNA methylation impacts HOX genes expression in bone marrow mesenchymal stromal cells of myelodysplastic syndromes and de novo acute myeloid leukemia. Cancer Gene Ther 2022, 29:1263
- Mancini SJC et al. Deciphering tumor niches: lessons from solid and hematological malignancies. Front Immunol 2021, 12:766275
- Vignon C et al. Involvement of GPx-3 in the reciprocal control of redox metabolism in the leukemic niche. Int J Mol Sci 2020, 21:8584
- Kouzi F et al. Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells. Oncogene 2019, 39:1198
Vice President
Fatima MECHTA-GRIGORIOU, PhD
Research Director INSERM
Institut Curie, Paris
INSERM U1339 / CNRS UMR3666
fatima.mechta-grigoriou@curie.fr
https://curie.fr/equipe/mechta-grigoriou
- Croizer H*, Mhaidly R*, et al. Deciphering the spatial landscape and plasticity of immunosuppressive fibroblasts in breast cancer. Nat Commun 2024, 15:2806
- Licaj M*, Mhaidly R*, et al. Residual ANTXR1+ myofibroblasts after chemotherapy inhibit anti-tumor immunity via YAP1 signaling pathway. Nat Commun 2024, 15:1312
- Cohen C, et al. WNT-dependent interaction between inflammatory fibroblasts and FOLR2+ macrophages promotes fibrosis in chronic kidney disease. Nat Commun 2024, 15:743
- Peltier A*, Seban RD* et al. Fibroblast heterogeneity in solid tumors: From single cell analysis to whole-body imaging. Semin Cancer Biol 2022, 86:262
- Kieffer Y, et al. Single cell analysis reveals fibroblast clusters linked to immunotherapy resistance in cancer. Cancer Discov 2020, 10:1330
Vice President
Véronique MAGUER-SATTA, PhD
Research Director CNRS
Cancer Research Center of Lyon, Lyon
CNRS UMR5286 / INSERM U1052
veronique.maguer-satta@cnrs.fr
https://www.crcl.fr/en/citi-department/bmp-ecosystem-stemness-and-dynamic-in-cancer/
- Zylbersztejn F et al. Human myeloid differentiation by BMP4 signaling through the VDR pathway in acute myeloid leukemia. Cell Death Discov 2024, 10:325
- Guyot B et al. An early neoplasia index (ENI10), based on molecular identity of CD10 cells and associated stemness biomarkers, is a predictor of patient outcome in many cancers. Cancer Res Com 2023, 3:1966
- Voeltzel T, et al. A minimal standardized human bone marrow microphysiological system to assess resident cell behavior during normal and pathological processes. Biomat Sci 2022, 10:485
- Prunet A, et al. A new agarose-based microsystem to investigate cell response to prolonged confinement. Lab Chip 2020, 20:4016
- Risson E et al. The current paradigm and challenges ahead for the dormancy of disseminated tumor cells. Nat Cancer 2020, 1:672
Secretary
Nathalie MAZURE, PhD
Research Director CNRS
Mediterranean Center for Molecular Medicine , Nice
INSERM U1065
mazure@univ-cotedazur.fr
- Fabbri L et al. Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell renal cell carcinoma patients. Theranostics 2020, 10:2696
- Meyenberg Cunha-de Padua M et al. Evidences of a rirect relationship between cellular fuel supply and ciliogenesis regulated by hypoxic VDAC1-ΔC. Cancers (Basel) 2020, 12:3484
- Bai H et al. Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency. Sci Transl Med 2020, 12:eaax7613
- Fabbri L et al. Primary cilium in cancer hallmarks. Int J Mol Sci 2019, 20:1336
- Brahimi-Horn MC et al. Local mitochondrial-endolysosomal microfusion cleaves the voltage-dependent anion channel 1 to promote survival in hypoxia. Mol Cell Biol 2015, 35: 1491
Deputy Secretary
Karl BALABANIAN, PhD
Research Director INSERM
Saint Louis Research Institute, Paris
INSERM U1160
Université Paris Cité
https://www.balabanian-espeli-lab.com/
- Debureaux PE et al. Inflammatory Waldenström Macroglobulinemia is associated with clonal hematopoiesis: a multicentric cohort. Blood 2025, 145:450
- Rondeau V et al. CXCR4 signaling determines the fate of hematopoietic multipotent progenitors by stimulating mTOR activity and mitochondrial metabolism. Sci Signal 2024, 17:eadl5100
- Anginot A et al. WHIM Syndrome-linked CXCR4 mutations drive osteoporosis. Nat Commun 2023, 14:2058
- Boy M et al. Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation. Nat Commun 2023, 14:588
- Alouche N et al. Hematological disorder associated Cxcr4-gain-of-function mutation leads to uncontrolled extrafollicular immune response. Blood 2021, 137:3050
Treasurer
Stéphane MANCINI, PhD
Research Director INSERM
INSERM U1236 MOBIDIC, Rennes
stephane.mancini@univ-rennes1.fr
https://mobidic.univ-rennes1.fr/project-4-bone-marrow-supportive-niches-b-all
- Touarin P et al. Pre-B cell receptor acts as a selectivity switch for galectin-1 at the pre-B cell surface. Cell Rep 2024, 43:114541
- Rondeau V et al. CXCR4 signaling determines the fate of hematopoietic multipotent progenitors by stimulating mTOR activity and mitochondrial metabolism. Sci Signal 2024, 17:eadl5100
- Fregona V et al. Stem cell-like reprogramming is required for leukemia-initiating activity in B-ALL. J Exp Med 2024, 221:e20230279
- Pelletier J et al. Niche-expressed Galectin-1 is involved in pre-B acute lymphoblastic leukemia relapse through pre-B cell receptor activation. iScience 2023, 26:106385
- Delahaye MC et al. Toward Therapeutic Targeting of Bone Marrow Leukemic Niche Protective Signals in B-Cell Acute Lymphoblastic Leukemia. Front Oncol 2021, 10:606540
Deputy Treasurer
Gwendal LAZENNEC, PhD
Research Director CNRS
CNRS UMR9005 SYS2DIAG, Montpellier
gwendal.lazennec@sys2diag.cnrs.fr
http://gwendal.lazennec.free.fr/
- Lazennec G et al. CXCR2 chemokine receptor – a master regulator in cancer and physiology. Trends Mol Med 2024, 1: 37
- Anginot A et al. WHIM Syndrome-linked CXCR4 mutations drive osteoporosis. Nat Com 2023, 14:2058
- Delobel P et al. CXCR2 intrinsically drives the maturation and function of neutrophils in mice. Front Immunol 2022, 13: 1005551
- Timaxian C et al. Pivotal role for Cxcr2 in regulating tumor-associated neutrophil in breast cancer. Cancers (Basel) 2021, 13:2584
- Boissière-Michot F et al. CXCR2 levels correlate with immune infiltration and a better prognosis of triple negative breast cancers. Cancers (Basel) 2021, 13: 2328
Councillor
Marie-Caroline Le BOUSSE-KERDILES, PhD
Research Director INSERM
INSERM UMRS-MD1197, Villejuif
caroline.le-bousse-kerdiles@inserm.fr
- Guarrigue A et al. Human Oncostatin M deficiency underlies an inherited severe bone marrow failure syndrome. J Clin Invest 2025, Jan 23:e180981
- Voeltzel T, et al. A minimal standardized human bone marrow microphysiological system to assess resident cell behavior during normal and pathological processes. Biomat Sci 2022, 10:485
- Tseng HW et al. Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles. Bone Res 2022, 10:22
- Mancini SJC et al. Deciphering tumor niches: lessons from solid and hematological malignancies. Front Immunol 2021, 12:76627
- Vignon C et al. Involvement of GPx-3 in the reciprocal control of redox metabolism in the leukemic niche. Int J Mol Sci 2020, 21:E8584